Bioavailability and Cardiovascular Effects of Adrenaline Administered by Anapen Autoinjector in Healthy Volunteers.
Identifieur interne : 001102 ( Main/Exploration ); précédent : 001101; suivant : 001103Bioavailability and Cardiovascular Effects of Adrenaline Administered by Anapen Autoinjector in Healthy Volunteers.
Auteurs : Thierry Duvauchelle [France] ; Philippe Robert [France] ; Yves Donazzolo [France] ; Sabrina Loyau [France] ; Bernard Orlandini [France] ; Philippe Lehert [Australie] ; Jeanne-Marie Lecomte [France] ; Jean-Charles Schwartz [France]Source :
- The journal of allergy and clinical immunology. In practice [ 2213-2201 ] ; 2017.
Abstract
The administration of adrenaline is a life-saving intervention for anaphylactic reactions. However, it has been questioned whether the needle length of the autoinjectors is sufficient to achieve genuine intramuscular delivery and optimal bioavailability.
DOI: 10.1016/j.jaip.2017.09.021
PubMed: 29109047
Affiliations:
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<front><div type="abstract" xml:lang="en">The administration of adrenaline is a life-saving intervention for anaphylactic reactions. However, it has been questioned whether the needle length of the autoinjectors is sufficient to achieve genuine intramuscular delivery and optimal bioavailability.</div>
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